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Max-Prostate Specialist

Scientific Research Publications

Our bodies produce and process a variety of enzymes and chemicals for optimum health. Here in lies the secret we have found, that a particular enzyme called HETE, without which the cancer cells in the prostate cannot survive. Simply put, HETE is the only essential food that prostate cancer cells eat – it sort of like you finding the “essential carrot” for the “malignant rabbits” that wants to kill you. So the next question is how can we prevent HETE? Well our research turns up that an enzyme 5 LO (lypo oxygenase) makes HETE. So here is the GREAT NEWS in a nutshell – NO 5 LO – NO HETE – NO PROSTATE CANCER. GOT IT?

Published Medical Journal Research:
Dr Gosh J (Univ Virginia Cancer Ctr) Dr. Herzenber LA (Stanford Univ. Med School) Inhibition of arachidonic 5-Lypoxygenese triggers massive apoptosis in human prostate cancer cells. Proc Nat’l Acad Sci USA 1998 October 27; 95 (22) 13182-13187
Report said that inhibition of 5 LO completely blocks 5 HETE production and induces massive cancer cell death to hormone responsive as well as hormone non responsive human prostate cancer cells. It continues “the critical role of 5 LO in prostate cancer cell life”. Dr. Zhang confirmed the study at Nat’l Acad Sci 1992, Dr. Stockton et al also confirmed likewise on Mol Bio/Cell 2001.

A. BETA-SITOSTEROL is a standardized combination of plant phytosterols found in vegetables and herbs.

1. Dr. Klippel et al, University Dresden, Germany
This double blind study involving 177 men with BPH ran for 6 months, quite a substantial research with 32 references concluded “These results show that Beta Sitosterol is an effective option in the treatment of BPH”. Brit.J. Urol 1997 Sept. ’80: 427-32
2. Dr. Bernges et al, University of Bochum, Germany
This large double blind 200 men 1 year study said “significant improvement and urinary flow parameters show effectiveness of Beta Sitosterol in BPH” By far one of the BEST research published. Lancet 1995 Jun 17. 354 1929-32.
3.Veteran Hospital of Minneapolis, USA
Reviewed 30 years and 32 researches concluded that beta Sitosterol “The greatest efficacy among phyto therapeutic substances” and Beta Sitosterol improves urological symptoms and flow measures.

B. ZINC - This is a crucial and vital micronutrient for a healthy prostate, because zinc has its highest concentration in the prostate on human being. And yet our diet is sorely deficient in zinc causing terrible tissue damage to the prostate. It has been widely studied and published research in Journal of Steroid Biochemistry, and Kliniche Endokninologya (Germany).

1. Dr. Chang G.T. et al “Characterization of a zinc funger protein and its association with Apoptosis in prostate cancer cell”. J. Nati Lancer list Sept 6, 92 :1414-21. Showing zinc and protein effect on prostate cancer cell natural death.

C. GREEN TEA – A special catechin compound bio-active called Epigallocatechin Gallate (EGCG for short) has been found to be a new herbal polyphenol extract breakthru.

1. Dr. Pashce et al “Induction of Apoptosis in prostate cancer by green tea ECGC”. Cancer letter 1998:130:1-7
2. Dr. Hilpakka R.A. et al “Structure Activity Relationship for inhibition of human 5- alpha- Reductase by polyphenol” Biochem Pharmacol 2002 Mar 15; 63:1165-76
3. Dr. Gupta S. “Inhibitation of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols” Proc Nat’l Acad. Science USA 2001 Aug 28:98:10350-5
4. Dr. Lyn-Cook B.D. “Chemo preventive effect of tea extract and various components on human pancreatic and prostate tumor cell in vitro” Nutr. Cancer 1999; 35:80-6

D. SAW PALMETTO - Known by it’s Latin name (Serenoa Repens) is a small palm tree native to Florida. The fruits and berries were eaten by the Seminole Indians and have been used since 1800’s by physicians to treat various kinds of urinary problems.

1. Dr. Mark L.S. “Tissue effects of Saw Palmetto and Finasteride: Use of Biopsy cones for in situ Quantification of Prostatic Androgen” J. Urology 2001; 57:999-1005. This study showed a double blind clinical result of men taking Saw Palmetto had 32% less DHT- a hormone associated with BPH- in 6 months treatment concluding that Saw Palmetto may be an effective treatment for reducing the symptoms of BPH said Dr. Marks director of Urological Sciences Research Foundation. This is a very important study, said Dr. Blumenthal, founder of American Botanical Council, a non profit organization.
2. Dr. Wilt T.J. et al, Saw Palmetto extract for treatment of benign Prostatic Hyperplasia: A systemic Review. JAMA 1998:280 (18):1604- 1609

E. BOSWELLIA SERRATA - Frankincence used to be more expensive than Gold, the same as one of the gifts from the 3 Kings of the Orient to pay homage to Jesus when he was born, Prized for thousands of years in herbal medicine Inhibits 5 LO.

1. Dr. Safayhi H et al Boswellia acids, novel, specific, redox inhibitors of 5-lipoxygenase. J. Pharmacol Exp Ther 1992 Jun:261(3) 1143-6 shows specifically a new Boswellia to inhibit 5-LO.
2. Dr. Ammon H.P. et al Mechanism of anti inflammatory actions of curcumina and boswellic acid. J. Ethno pharmacol (993 Mar; 38 (2-3):113-9
3. Dr. Huang M.T. et al Anti tumor and anti-carcinogenic activities of triterpenoid, beta-boswellic acid. Biofactors. 2000:13:225-30 this research narrowed a specific molecule of triterpene in the boswellic acid that stops cancer.
4. Dr. Jakoksson P. et al On the expression and regulation of 5-Lipoxygenses (5-LO) in human Lymphocytes. Proc Natl. Acad Sci USA 1992 April 15 89 (8):3521-5

F. SCUTTELLARIA BAICALIN – Ancient Chinese root herb that has been used to heal and tonify.

1. Dr. Chan et al Induction of Apoptosis in prostate cancer cells by flavonoid baicalin. Very prestigious Cancer letter 2000.

G. LICORICE - Another herb is a root used all over the world has many powerful compounds.

1. Nat. cancer Institute 1999 International Conference. New compound extracted from licorice root shows antitumor activity in acute leukemia, breast cancer and prostate cancer.

H. GINGER - USDA Phytonutrient Database shows strong 5-LO inhibition by Ginger in a special standardized critical extract showed ability to inhibit 5-LO. It was over 20 compounds to inhibit 5-LO.

I. PANAX GINSENG – Probably the oldest and most used herb in the world as a tonic, anti-aging, and anti-fatigue. It is also one of the most researched herb with volumes of publication. Shows specific activity against prostate cancer.

1. Dr. Liu et al Autiproliferative effect of Ginseng saponim on human prostate cancer cell live. Life Science 2000 Aug 4:67(11):1297-306 Research shows the ability of ginseng to work on interfering with 5- alpha reductase to stop production of DHT.
2. Dr. Fahim et al Effect of Panex Ginseng on testosterone level and prostate in Rats. Arch Androl 1982 Jun,8 (4):261-3 This remarkable research showed the intake of Panax Ginseng actually decreased the size and weight of the prostate while increasing testosterone level for higher libido and sexual functions.

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