Published Medical Journal Research:
Dr Gosh J (Univ Virginia Cancer
Ctr) Dr. Herzenber LA (Stanford Univ. Med School) Inhibition
of arachidonic 5-Lypoxygenese triggers massive apoptosis
in human prostate cancer cells. Proc Nat’l Acad
Sci USA 1998 October 27; 95 (22) 13182-13187
Report said that inhibition of 5 LO completely blocks 5 HETE production and
induces massive cancer cell death to hormone responsive as well as hormone
non responsive human prostate cancer cells. It continues “the critical
role of 5 LO in prostate cancer cell life”. Dr. Zhang confirmed the
study at Nat’l Acad Sci 1992, Dr. Stockton et al also confirmed likewise
on Mol Bio/Cell 2001.
A. BETA-SITOSTEROL is
a standardized combination of plant phytosterols found
in vegetables and herbs.
1. Dr. Klippel et al,
University Dresden, Germany
This double blind study involving 177 men with BPH ran for 6 months, quite
a substantial research with 32 references concluded “These results
show that Beta Sitosterol is an effective option in the treatment of BPH”.
Brit.J. Urol 1997 Sept. ’80: 427-32
2. Dr. Bernges et al, University of Bochum, Germany
This large double blind 200 men 1 year study said “significant improvement
and urinary flow parameters show effectiveness of Beta Sitosterol in BPH” By
far one of the BEST research published. Lancet 1995 Jun 17. 354 1929-32.
3.Veteran Hospital of Minneapolis, USA
Reviewed 30 years and 32 researches concluded that beta Sitosterol “The
greatest efficacy among phyto therapeutic substances” and Beta Sitosterol
improves urological symptoms and flow measures.
B. ZINC - This
is a crucial and vital micronutrient for a healthy prostate,
because zinc has its highest concentration in the prostate
on human being. And yet our diet is sorely deficient
in zinc causing terrible tissue damage to the prostate.
It has been widely studied and published research in
Journal of Steroid Biochemistry, and Kliniche Endokninologya
(Germany).
1. Dr. Chang G.T. et
al “Characterization of a zinc funger protein and
its association with Apoptosis in prostate cancer cell”.
J. Nati Lancer list Sept 6, 92 :1414-21. Showing zinc
and protein effect on prostate cancer cell natural death.
C. GREEN
TEA – A special catechin compound
bio-active called Epigallocatechin Gallate (EGCG
for short) has been found to be a new herbal polyphenol
extract breakthru.
1. Dr. Pashce et al “Induction
of Apoptosis in prostate cancer by green tea ECGC”.
Cancer letter 1998:130:1-7
2. Dr. Hilpakka R.A. et al “Structure Activity Relationship for inhibition
of human 5- alpha- Reductase by polyphenol” Biochem Pharmacol 2002
Mar 15; 63:1165-76
3. Dr. Gupta S. “Inhibitation of prostate carcinogenesis in TRAMP mice
by oral infusion of green tea polyphenols” Proc Nat’l Acad. Science
USA 2001 Aug 28:98:10350-5
4. Dr. Lyn-Cook B.D. “Chemo preventive effect of tea extract and various
components on human pancreatic and prostate tumor cell in vitro” Nutr.
Cancer 1999; 35:80-6
D. SAW PALMETTO -
Known by it’s Latin name (Serenoa Repens) is a
small palm tree native to Florida. The fruits and berries
were eaten by the Seminole Indians and have been used
since 1800’s by physicians to treat various kinds
of urinary problems.
1. Dr. Mark L.S. “Tissue
effects of Saw Palmetto and Finasteride: Use of Biopsy
cones for in situ Quantification of Prostatic Androgen” J.
Urology 2001; 57:999-1005. This study showed a double
blind clinical result of men taking Saw Palmetto had
32% less DHT- a hormone associated with BPH- in 6 months
treatment concluding that Saw Palmetto may be an effective
treatment for reducing the symptoms of BPH said Dr. Marks
director of Urological Sciences Research Foundation.
This is a very important study, said Dr. Blumenthal,
founder of American Botanical Council, a non profit organization.
2. Dr. Wilt T.J. et al, Saw Palmetto extract for treatment of benign Prostatic
Hyperplasia: A systemic Review. JAMA 1998:280 (18):1604- 1609
E. BOSWELLIA SERRATA -
Frankincence used to be more expensive than Gold, the
same as one of the gifts from the 3 Kings of the Orient
to pay homage to Jesus when he was born, Prized for thousands
of years in herbal medicine Inhibits 5 LO.
1. Dr. Safayhi H et al
Boswellia acids, novel, specific, redox inhibitors of
5-lipoxygenase. J. Pharmacol Exp Ther 1992 Jun:261(3)
1143-6 shows specifically a new Boswellia to inhibit
5-LO.
2. Dr. Ammon H.P. et al Mechanism of anti inflammatory actions of curcumina
and boswellic acid. J. Ethno pharmacol (993 Mar; 38 (2-3):113-9
3. Dr. Huang M.T. et al Anti tumor and anti-carcinogenic activities of triterpenoid,
beta-boswellic acid. Biofactors. 2000:13:225-30 this research narrowed a
specific molecule of triterpene in the boswellic acid that stops cancer.
4. Dr. Jakoksson P. et al On the expression and regulation of 5-Lipoxygenses
(5-LO) in human Lymphocytes. Proc Natl. Acad Sci USA 1992 April 15 89 (8):3521-5
F. SCUTTELLARIA
BAICALIN – Ancient Chinese root
herb that has been used to heal and tonify.
1. Dr. Chan et al Induction
of Apoptosis in prostate cancer cells by flavonoid baicalin.
Very prestigious Cancer letter 2000.
G. LICORICE -
Another herb is a root used all over the world has many
powerful compounds.
1. Nat. cancer Institute
1999 International Conference. New compound extracted
from licorice root shows antitumor activity in acute
leukemia, breast cancer and prostate cancer.
H. GINGER - USDA
Phytonutrient Database shows strong 5-LO inhibition by
Ginger in a special standardized critical extract showed
ability to inhibit 5-LO. It was over 20 compounds to
inhibit 5-LO.
I. PANAX GINSENG – Probably
the oldest and most used herb in the world as a tonic,
anti-aging, and anti-fatigue. It is also one of the most
researched herb with volumes of publication. Shows specific
activity against prostate cancer.
1. Dr. Liu et al Autiproliferative
effect of Ginseng saponim on human prostate cancer cell
live. Life Science 2000 Aug 4:67(11):1297-306 Research
shows the ability of ginseng to work on interfering with
5- alpha reductase to stop production of DHT.
2. Dr. Fahim et al Effect of Panex Ginseng on testosterone level and prostate
in Rats. Arch Androl 1982 Jun,8 (4):261-3 This remarkable research showed
the intake of Panax Ginseng actually decreased the size and weight of the
prostate while increasing testosterone level for higher libido and sexual
functions.
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